项目

Are pesticides a health hazard for farmers?

Evaluating potential hazards for the Agricultural Health Study (AHS)

挑战

Despite a lower overall mortality rate than the general population, farmers experience an excess of certain cancers, 比如白血病, 骨髓瘤, 非霍奇金淋巴瘤, 还有唇癌, 胃, 皮肤。, 大脑, 和前列腺. 其他条件, 像哮喘, 神经系统疾病, and adverse reproductive outcomes may also be related to agricultural exposures.

The National Cancer Institute, the National Institute of Environmental Health Sciences, and the Environmental Protection Agency launched the Agricultural Health Study (AHS) in 1993 to evaluate a connection between these health outcomes and potentially hazardous substances prevalent in farming communities.

解决方案

自2002年以来, 趣赢平台 has followed nearly 90,000 registered pesticide applicators in Iowa and North Carolina and their spouses to determine how environmental exposures from pesticide application may put them at increased risk for cancer. The study will also investigate the role of lifestyle, 饮食, and genetic factors as contributors to cancer risk.

As the coordinating center, we develop the annual study update, maintain the master database of study participants and participation in substudies, 跟踪参与者, identify and verify disease outcomes, and build analytic datasets. Previously we collected biospecimens, 灰尘, and GPS measurements for a biomarker substudy within the AHS that was completed in 2018. Since the completion of that substudy, we have been building analytic datasets and tracking specimens and requests for specimens.

结果

This research will identify factors that affect the risk of various types of cancers and other adverse health conditions in farming populations.

The list of publications for the AHS is available at http://aghealth.nih.gov /News/出版物.html.

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